Extensive reorganization of primary somatosensory cortex in chronic back pain patients

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Extensive reorganization of primary somatosensory cortex in chronic back pain patients.

The hypothesis of reorganization of the primary somatosensory cortex in states of chronic pain was assessed in 10 low back pain patients and nine matched healthy controls. Intracutaneous electric stimuli were applied to the left back and index finger at a standard, a non-painful and a painful intensity. Magnetic fields were recorded by a 37-channel BTi biomagnetometer from the hemisphere contra...

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Reorganization in Secondary Somatosensory Cortex in Chronic Low Back Pain Patients.

STUDY DESIGN A cross-sectional comparative study between chronic low back pain (CLBP) patients and healthy control subjects. OBJECTIVE The aim of this study was to investigate reorganization in the sensory cortex by comparing cortical activity due to mechanosensory stimulation of the lumbar spine in CLBP patients versus a control group by using functional magnetic resonance imaging (fMRI). ...

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Primary somatosensory cortex in chronic low back pain – a 1H-MRS study

The goal of this study was to investigate whether certain metabolites, specific to neurons, glial cells, and the neuronal-glial neurotransmission system, in the primary somatosensory cortex (SSC), are altered and correlated with clinical characteristics of pain in patients with chronic low back pain (LBP). Eleven LBP patients and eleven age-matched healthy controls were included. N-acetylaspart...

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Primary somatosensory cortex in chronic low back pain â•fi a 1H-MRS study

somatosensory cortex in chronic low back pain – a 1H-MRS study. Abstract: The goal of this study was to investigate whether certain metabolites, specific to neurons, glial cells, and the neuronal-glial neurotransmission system, in the primary somatosensory cortex (SSC), are altered and correlated with clinical characteristics of pain in patients with chronic low back pain (LBP). Eleven LBP pati...

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Thalamocortical connections of the primary somatosensory cortex

  Although each subdivision of primary somatosensory cortex (SI) receives dense input from the thalamus, but the exact location and type of information that the fibers convey have not been identified yet. In the present study, the exact source of thalamocortical fibers to areas 2 and 3b was investigated using tract-tracing techniques. Following injection of tracer into area 3b, labeled neurons ...

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ژورنال

عنوان ژورنال: Neuroscience Letters

سال: 1997

ISSN: 0304-3940

DOI: 10.1016/s0304-3940(97)13441-3